Ibuprofen 400mg is a painkiller used to relieve pain caused by:

• Period pain
• Nerve pain 
• Dental pain 
• Headaches and migraines 
• Swollen and stiff joints
• Arthritis
• Cold and flu symptoms  

They also help to reduce swelling and fever. Each tablet contains 400mg, which is twice as strong as regular ibuprofen.

How Ibuprofen 400mg tablets work

Ibuprofen belongs to a group of medicines known as non-steroidal anti-inflammatory drugs (NSAIDs).

The medicine works by changing how your body reacts to pain. It reduces hormones that cause pain and swelling.

Directions

Always take Ibuprofen exactly as described in the patient information leaflet or as your doctor / pharmacist has told you. 

Take 1 tablet up to 3 times a day. Take with a glass of water, preferably with or after food. Do not take more than 3 tablets in 24 hours.

Side effects

Like all medicines, Ibuprofen may cause side effects in some people, but these won’t affect everybody. Common side effects include: 

• Nausea and vomiting 
• Diarrhoea, gas, bloating, constipation
• Worsening of ulcers in the rectum and colon 
• Worsening inflammation of the digestive system 
• Inflammation or irritation of the lining of the stomach
• Indigestion 
• A small increased risk of heart attack or stroke
• Hypertension

If you experience any side effects, including any not included in the patient information leaflet, you can report them using the MHRA Yellow Card Scheme.

Serious side effects

Seek emergency medical attention if you notice any signs of a severe allergic reaction, symptoms of which include swelling of the face and throat, skin rash, breathing difficulties and/or loss of consciousness.

Warnings

Ibuprofen may be unsuitable for certain people. Do not take these tablets if you are allergic to any of the ingredients or if:

• You have asthma 
• You have liver disease
• You have kidney disease
• You have heart disease
• You have ever had a peptic ulcer 
• You have ever had bleeding in your digestive tract
• You have swelling of the hands, feet, arms, ankles or lower legs
• You get blurred vision, blind spots or changes in colour vision

Talk to your doctor or pharmacist before taking this medicine if: 

• You have diabetes 
• You have high blood pressure
• You have previously had a stroke
• You have high cholesterol
• You have an infection

Using/taking other medicines

Speak to your healthcare provider if you are taking or have recently taken any other medication, including medication obtained without a prescription. Ibuprofen may affect or be affected by other medications, for example:

• Aspirin or other non-steroidal anti-inflammatory drugs for pain relief 
• Corticosteroids e.g. hydrocortisone 
• Quinolones e.g. ciprofloxacin 
• Ginkgo biloba 
• Cardiac glycosides 
• Diuretics 
• Ciclosporin or tacrolimus 
• Lithium or digoxin 
• Selective serotonin reuptake inhibitors (SSRIs) e.g. fluoxetine 
• Mifepristone
• Methotrexate 
• Medicines to treat HIV e.g. zidovudine 
• Glibenclamide 
• Medicines used to treat fungal infections e.g. voriconazole or fluconazole
• Anticoagulant medication e.g. warfarin 
• Medicines that reduce high blood pressure    

Age restrictions 

This medication should not be taken by children under 12.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, you must ask your doctor or pharmacist for advice before taking any new medicine.  Ibuprofen is not recommended during pregnancy. Do not take this medicine in the last 3 months of pregnancy. 

Fertility risks

Ibuprofen belongs to a group of medicines that can lower your chances of becoming pregnant. Your fertility rate should return to normal when you stop taking this medication.

Storage information

Store under 25°C in a cool, dry place out of sight and reach of children. Do not use after the expiry date, referring to the last day of the month stated on the packaging. Do not throw away any medicines via wastewater or household waste.

Important information

This product is a medicine; make sure to speak to your doctor or pharmacist before taking this product if you have an underlying medical problem or are taking any other medicine or complementary therapy. If your symptoms get worse or continue after taking this product, contact us or your doctor. For medical services in your area, please refer to https://www.nhs.uk

If you are pregnant, trying to become pregnant, or breastfeeding, speak to your doctor or pharmacist before taking this product. If you suffer from any allergies, ask your doctor or pharmacist if this medicine is right for you.

Store all medicines out of sight and reach of children.

Please read the included leaflet carefully before taking this product.

Please contact your GP if appropriate regarding this product.